Exploring the frontiers
of nasal, sinus, and
upper airway biology
Our laboratory includes basic science and translational research with two main areas of interest:
- understanding the nasal epithelium in health and disease, and
- promoting upper airway mucosal regeneration in response to injury from surgery, chemicals, and toxins in human and animal model systems.
Our research also includes understanding nasal immune system dysfunction in patients with chronic diseases such as cystic fibrosis and rhinosinusitis.
The ultimate goal of our efforts is to more effectively treat debilitating inflammatory sinus disorders, particularly with regard to empty nose syndrome (ENS) and to create functional respiratory mucosal tissue grafts/lining material to address upper (nasal) and lower (pulmonary) airway diseases.
Our Funding and Support
CA Institute of Regenerative Medicine (CIRM) 2017-2019 Co-I with Drs. Matthew Porteus, Calvin Kuo, Tushar Desai
Philanthropic Support: Anonymous Donor Support
NIH/Cooperative Centers for Translational Research on Human Immunology and Biodefense (CCHI)
CCHI – “Influenza virus tropism for human nasal epithelial basal cells of the upper airway.”