Research

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We are committed to increasing our pre-surgical armamentarium to combat the pervasive problems with inflammatory sinus disease, to make sinus surgery both less common overall, but also safer when performed. Rhinology is still in an emerging specialty when compared to other disciplines like cardiac and ophthalmologic surgery, which have a smorgasbord of medical and minimally-invasive procedural options available prior to surgery.

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Our lab focuses on disorders of nasal physiology and nasal breathing, particularly with regard to the debilitating disease termed empty nose syndrome (ENS). Our practice of >100 patients with ENS has allowed the design and validation of what are now considered gold standard subjective (ENS6Q) and provocative (nasal cotton test) tests to more accurately identify patients suffering from ENS.

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The innate and adaptive immunologic microenvironment in chronic human upper airway diseases like chronic rhinosinusitis (CRS) has also been of ongoing interest of our group.

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Upper airway diseases of the nasal cavity and sinuses create significant morbidities and socioeconomic burdens. These include the many forms of chronic rhinosinusitis (CRS), which afflict 10% of the US population, the rare but debilitating breathing disorder termed empty nose syndrome (ENS, described under a different heading, and cystic fibrosis (CF), the #1 most lethal genetic disease in the world. diseases. 

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